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手术方式对乳腺癌患者术后早期上肢功能及身心状态的影响

Effects of surgical approaches on early postoperative upper limb function and psychophysical status in breast cancer patients

  • 摘要:
    目的  探讨保乳手术(breast-conserving surgery, BCS)、单纯切除术(simple mastectomy, SM)及改良根治术(modified radical mastectomy, MRM)3种不同手术方式对乳腺癌患者术后早期上肢功能及身心状态的影响。
    方法 采用横断面研究设计,选取2024年10月至2025年12月在福建医科大学附属漳州市医院乳腺外科手术的212例女性乳腺癌患者。根据手术方式分为BCS组(n=34)、SM组(n=79)和MRM组(n=99),收集患者一般资料。术后3~7 d(窗口期),采用Constant-Murley肩关节评分(Constant-Murley score, CMS)、肩关节主动活动度(active range of motion, AROM)及DASH简式评分表(The Quick Disabilities of the Arm, Shoulder and Hand, QuickDASH)评估上肢功能;采用广泛性焦虑量表(Generalized Anxiety Disorder-7, GAD-7)、9项患者健康问卷(Patient Health Questionnaire-9, PHQ-9)、乳腺癌患者生命质量测定量表(Functional Assessment of Cancer Therapy-Breast, FACT-B)及匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index, PSQI)评估心理、生活质量及睡眠状况。
    结果 BCS组CMS总分、疼痛程度评分、关节活动范围评分高于SM组和MRM组(P<0.05);BCS组前屈活动度大于SM组和MRM组(P<0.05),SM组内旋活动度小于MRM组和BCS组(P<0.05)。BCS组患者的PHQ-9抑郁评分高于MRM组(P<0.05)。3组在QuickDASH、GAD-7、FACT-B及PSQI评分上的差异无统计学意义。
    结论 接受不同术式的乳腺癌患者在术后躯体功能与心理状态上表现出差异。BCS能较好保留术后早期上肢功能,但患者抑郁评分较高。

     

    Abstract:
    Objective To explore the effects of breast-conserving surgery (BCS), simple mastectomy (SM), and modified radical mastectomy (MRM) on early postoperative upper limb motor function, physical function and psychological status in breast cancer patients.
    Methods A cross-sectional study design was employed. A total of 212 female breast cancer patients undergoing surgery at the Department of Breast Surgery of Zhangzhou Affiliated Hospital of Fujian Medical University from October 2024 to December 2025 were enrolled. Patients were divided into the BCS group (n=34), SM group (n=79), and MRM group (n=99). General demographic and clinical data were collected. At 3–7 days postoperatively (window period), the Constant-Murley score (CMS), active range of motion (AROM) of the shoulder joint, and the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score were used to assess upper limb function; the Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), Functional Assessment of Cancer Therapy-Breast (FACT-B), and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate psychological status, quality of life, and sleep quality.
    Results The total CMS score, pain score, and range of motion score in the BCS group were higher than those in the SM and MRM groups (P<0.05). The BCS group showed greater forward flexion range of motion than the SM and MRM groups (P<0.05); and the SM group showed smaller internal rotation range of motion than the MRM and BCS groups (P<0.05). The PHQ-9 depression score in the BCS group was significantly higher than that in the MRM group (P<0.05). There were no statistically significant differences among the three groups in QuickDASH, GAD-7, FACT-B, or PSQI scores.
    Conclusions Breast cancer patients undergoing different surgical procedures exhibit differences in postoperative physical function and psychological status. BCS can better preserve early postoperative upper limb function but may be associated with a certain tendency toward depression.

     

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